趙博士主要從事tau蛋白?。ㄈ绨柎暮Ｄ?、進(jìn)行性核上性麻痹等）的分子機(jī)制研究。以他為第一作者的多項(xiàng)研究成果發(fā)表在Neuron, Journal of Experimental Medicine等國際知名刊物上，并多次被國內(nèi)外各大媒體報(bào)道。從2015年至今為多個(gè)國際知名雜志審稿（包括Molecular Neurodegeneration, Molecular Neurobiology, Journal of Alzheimer's Disease, , Plos One, Journal of Neural Transmission, Brain Research等）。
聯(lián)系方式：jun1874@163.com
代表性論文：
1．Zhao Y, Tseng IC, Heyser CJ, Rockenstein E, Mante M, Adame A, Zheng Q, Huang T, Wang X, Arslan PE, Chakrabarty P, Wu C, Bu G, Mobley WC, Zhang YW, St George-Hyslop P, Masliah E, Fraser P, Xu H. Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis. Neuron (featured article). 2015; 87(5):963-75.
2．Huang T*, Zhao Y*, Jiang LL, Li X, Liu Y, Sun Y, Pina-Crespo JC, Zhu B, Masliah E, Willnow TE, Pasquale EB, Xu H. SORLA attenuates EphA4 signaling and β-amyloid-induced neurodegeneration. The Journal of Experimental Medicine. 2017; 214(12): 3669-85*, co-first authors
3．Zhao Y, Li X, Huang T, Jiang LL, Zhang M, Cheng I HJ, Wang X, Bu G, Zhang YW, Wang Q, Xu H. Intracellular-trafficking of TREM2 is regulated by presenilin 1. Experimental Molecular Medicine. 2017; 49, e405.
4．Zhao Y*, Wu X*, Li X*, Jiang LL*, Gui X, Liu Y, Sun Y, Zhu B, Pina-Crespo JC, Zhang M, Zhang N, Chen X, Bu G, An Z, Huang TY, Xu H. TREM2 is a receptor for β-amyloid which mediates microglial function. Neuron. 2018;97(5):1023-31 *, co-first authors
5．Du Y*, Zhao Y*, Li C*, Zheng Q, Tian J, Li Z, Huang T, Zhang W, Xu H. Inhibition of PKCδ reduces amyloid-beta levels and reverses Alzheimer Disease phenotypes. The Journal of Experimental Medicine, 2018, DOI: 10.1084/jem.20171193 *, co-first authors
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